The weight loss medicine Accomplia has not been approved by the FDA, but is already drawing the attention of the public and scientists.
The latest Headlines Acomplia appear online in the Cochrance library.
The researchers included the postgraduate student Cintia Curioni, MSC, the Brazilian University of Rio de Janeiro.They reviewed four studies on the use of accomplia in more than 6,600 adults with overweight and obese.
For a year or two, participants took over as higher or lower doses (20 milligrams or 5 daily milligrams) or pills that do not contain medicinal products (placebo).
But they not just pop pills. They also shaved about 600 calories out of their daily diet.
Camps For Weight Loss For Adults - Accomplia Shows 'Modest' Weight Loss
The key issue of studies: Who lost more weight?
The answer: Participants taking the highest dose of accomplia.
At the time of a year, they lost about 11 pounds, on average, than those who take placebo.
Dieters Taking the dose of the lowest lost accomplia almost 3 pounds more in a year than those that take placebo on average.
Both groups Acomplia trimmed their waists: by an inch and a half with the highest dose and half an inch with the lower dose.
People who take the highest dose also showed more improvement in blood pressure and cholesterol than those that take the lower dose or placebo.
But the highest dose of the accommodation may have come with more risks.
People who take the largest dose of the accommodia were more likely to have adverse effects, "especially the nervous, psychiatric system and gastrointestinal origin," Curioni's team writes.
On the one hand, "up modest amounts of weight loss can be potentially beneficial," writing Curioni and colleagues.
They note that people who take the highest dose of the accommodia had "modest weight loss of about 5%" of their body weight.
But, on the other hand, the reviewers ask caution in the interpretation of revision results.
They notice that about 40% of participants give up early studies and none of the studies met the highest standards of the reviewers.
The Curioni team calls longer and strict studies before making definitive recommendations on the use of the medicinal product in overweight and obese patients.Meanwhile, reviewers say that drug free methods "should remain the basis of obesitybesity therapy" in people who want to lose extra weight.
This may seem simple. But diet and exercise are often easier said than doing.
If you are interested in losing weight, consult your doctor to start a healthy weight loss plan.
Acomplia, which was approved in Europe, is made by the Sanofi-Aventis drug company. Sanofi-Aventis was not established in the name of the drug. FDA approval pending name. Sanofi-Aventis is a WebMD sponsor.
