Your genes can influence how you look at your skinny jeans.
Two studies identified 18 new genes linked to general obesity and 13 more influence if their weight goes to their belly or your thighs.
The discoveries come from the genetic investigation of the consortium of anthropometric traits (giant) and appear in the genetics of nature; If validated, they can play a role in how obesity is categorized and treated.
In the first study, the researchers performed an analysis of 46 studies of 123,865 people and identified 18 new genetic regions associated with the body mass index (BMI). They also confirmed 14 regions that had been observed before. Some of these genes affect appetite control and others can play a role in metabolism.
The more obesity genes that a person had, the greater the risk of being obese, showed the study. Individuals who performed 38 or more Genes associated with BMI weighed more than 15 to 20 pounds, on average, than those who had less than 22, researchers report. Still, these variants explain only a small fraction of the general variation in body weight, because many other genetic and environmental factors also contribute to the risk of obesity.
Oil For Belly Fat Loss - New Genes Linked to Obesity, Belly Fat
In the second study, the researchers analyzed 32 studies of 77,167 people to identify genes associated with the hyp-to-waist relationship, which is a measure of body fat distribution. Belly fat is a known risk factor for type 2 diabetes and heart disease, while fat stored on hips and thighs can actually be protective against diabetes and high blood pressure.
This study produced 13 large genes, and of these, seven genes had a more pronounced effect among women.
"We know 50% of our predisposition to weight is genetic and our study is trying to discover the subpinnings of this," says Elizabeth K . Speliotes, MD, PhD, MPH, a Medicine Instructor and Gastroenterology at Massachusetts General Hospital and a companion in the broad institute in Boston.
The new discoveries can help explain why the blanket recommendations about exercise and eat right just do not work for many people, she says.
"Most of these genes is completely romance, and this tells us that we do not really understand what we were dealing with in terms of obesity, so it is not surprising that most of our recommendations to control weight do not work," WebMD. "We hope that, with more work, we can restrict how these genes work and develop new ways to sub-class the obesity and tailor treatments."
"Genes carry the weapon, the environment pulls the trigger," says Scott Kahan, MD, co-director of the George Washington University Weight Management in Washington, D.C., in an email. "Even when we continue to educate people about obesity, healthy eating, physical activity, etc., ultimately we will not get too far until addressing the root cause of obesity / weight gain in our population."
and shortage of food), but now live in an environment that is very different from what our genes have evolved to do, "he says.
"We no longer have to hunt food, the food is incredibly available and the food is now" Engenharily to pack an incredible calorie density, the fomes are now essentially nonexistent in our population, and most of us You have to spend our days glued to a chair to meet the requirements of work and get our salary, "he says." This disconnection is at the root of obesity epidemic [and] besides teaching people about healthy behaviors and such, We need to approach the environment and, if possible, our genetic makeup. "
