by Dennis ThompsonHealthDay Reporter
Fat Loss Calorie Deficit - 'Brown Fat' May Help Your Health, Even if You're Obese
Monday, (Healthday News) - A special body fat seems to help protect against a series of chronic diseases, including heart disease, type 2 diabetes and high blood pressure, a new study suggests .
Brown fat generates heat, drawing the glucose of the bloodstream, as opposed to the white fat storage fat, explained Senior researcher of Dr. Paul Cohen. He is an assistant professor and medical senior attendants at the University Hospital of Rockefeller in New York.
This type of tissue sounds like a gift from God. However, brown fat has long been thought for a long time to have little impact on human health because its brown fat stores diminish as you age.
But the research now shows that adults who have active brown fatty fabrics in their bodies are far less likely than their peers to suffer from a range of chronic diseases.
What is more, this protective effect is even if the person carries the excess weight, the researchers recently reported in Nature Medicine magazine.
"When we group our subjects based on their body mass index, we have seen that even obese people with brown fat protection of these conditions," Cohen said.
"For example, it is well known that type 2 diabetes is more common in overweight and obese individuals, but what we have seen was that even obese individuals who have brown fat have a significantly lower probability of type diabetes 2 than obese individuals without brown fat, "he continued.
fat Brown is thought to be an evolutionary response to cold weather, helping to generate heat to maintain the central temperature of the body, the experts say.
"Babies can not shake, and so when they are cold, they could activate brown fat and stay hot in this way," said Ruth Loos, director of the genetics of obesity and the program of related metabolic traits At Charles R. Bronfman's Personalized Medicine Institute with ICAHN Medicine School on Mount Sinai in New York.
"For a long time, it was believed that he is present in babies, as he aged, he believed he would disappear," said Loos. "Now, with better ways to measure, we now know that it does not disappear totally in adults. Some people have a measurable amount of brown fat, which we did not know before."
Cohen said that studies performed about a decade ago "generated a lot of enthusiasm because they showed that adult human beings have brown fat that can be stimulated by cold exposure and that is functional, which means that it occupies glucose from the bloodstream."
brown fat is found in a layer of fat under the skin, typically in a region that extends from the base of the head and along the shoulders, and then by the spine, said Dr. Aaron Cialy, Chief From the translational physiology section of the diabetes agency, endocrinology and obesity of the US National Institute of Diabetes and Digestive and Renal Diseases.
Researchers can detect active brown fat stores using animal sweeps that are usually used to diagnose and accompany cancer looking for fabrics burning heavy glucose levels.
Cohen and his team held out his hand to the Memorial Sloan Kettering Cancer Center, obtaining more than 130,000 exams with more than 52,000 patients. They then reviewed these scans to look for brown fat deposits.
Almost 10% of the patients carried active brown fat, Cohen said. He added that this is likely to underestimate because the patients submitted to the sweeps were invited to avoid cold exposure, exercise and caffeine, all of which increase brown fat activity.The researchers verified the previous results on brown fat - these women are more likely to take you than men, that the amount of brown fat decreases as you age and gain weight, and this active brown fat is more likely to be found in cold versus hot weather sweeps.
But when the research team compared brown fat levels to patients' medical stories, they found new associations between brown fabric and better general health in people regardless of weight.
For example, people with active brown fat has improved levels of cholesterol and blood sugar. They were also less likely to have high cholesterol, coronary artery disease, congestive heart failure, high blood pressure and type 2.
"Some of these associations have never been documented before," Cohen said, although the study did not Definitely that brown fat causes the risk of disease fall.
It's still unclear why this link may exist, said CIAL.
"Is it through the simple process of burning and fat burning to keep it warm, or is brown fat acting as an endocrine organ that releases hormones in the blood and leads to these benefits?" Cialy said.
It's no cold to activate brown fat, Cohen watched - even a few hours in a 60 degree Fahrenheit room is enough.
This temperature "is cool, but it certainly is not Frigid," Cohen said. "I think it is intriguing from a public health perspective that simply lowering our thermostats for some degrees can result in health benefits."
Pharmaceutical companies are also looking for drugs that can activate brown fat and promote these benefits, Cohen said.
However, experts have agreed that very little is known about brown fat for anyone to try to lose weight or gain health benefits givillely in fresh or outdoor rooms.
."If you ate less at a meal, maybe it's better to drop some weight than trying to increase your brown fat," Cypess said. "I'll still tell the two things you need to do is eat a healthy meal plan and exercise, and hope we can bring brown fat activity on this plan."
More information
US National Health Institutes have more on brown fat.
Fonts: Paul Cohen, MD, PhD, Assistant Professor and Senior Attending Medical, University Hospital Rockefeller, New York; Ruth Loos, PhD, Director, Genetics of Obesity and Program of Related Metabolic Traces, Charles R. Personalized Medicine Institute of Bronfman, ICAHN Medicine School on Mount Sinai, New York; Aaron Cialy, MD, PhD, Head of Acting, Translational Physiology Section, Diabetes, Endocrinology and Obesity Branch, National Institute of Diabetes and Digestive Diseases and RIM; Medicine Nature, January 4, 2021, On-line
